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B4752

5-Bromocytosine

Name: 5-Bromocytosine
Brand: SIGMA

別名:

4-Amino-5-bromo-2-hydroxypyrimidine

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About This Item

実験式（ヒル表記法）:

C₄H₄BrN₃O

CAS番号:

2240-25-7

分子量:

190.00

Beilstein:

127286

EC Number:

218-806-8

MDL番号:

MFCD00056025

UNSPSCコード:

12352204

現在、価格および在庫状況を閲覧できません。

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mp

240-243 °C (dec.) (lit.)

SMILES記法

NC1=NC(=O)NC=C1Br

InChI

1S/C4H4BrN3O/c5-2-1-7-4(9)8-3(2)6/h1H,(H3,6,7,8,9)

InChI Key

QFVKLKDEXOWFSL-UHFFFAOYSA-N

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製品番号

詳細

価格

150649

5-Bromocytosine, 99%

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試験成績書（COA）

Lot/Batch Number

114H2623

097H2509

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Nine polymorphic crystal structures of d(CCGGGCCCGG), d(CCGGGCCm5CGG), d(Cm5CGGGCCm5CGG) and d(CCGGGCC(Br)5CGG) in three different conformations: effects of spermine binding and methylation on the bending and condensation of A-DNA.

D B Tippin et al.

Journal of molecular biology, 267(5), 1171-1185 (1997-04-18)

The A-DNA decamer d(CCGGGCCm5CGG) crystallizes in the presence of spermine in three polymorphic forms and with one duplex in the asymmetric unit: hexagonal (P6(1)), unit cell of 55.0 A x 55.0 A x 45.9 A; orthorhombic (P2(1)2(1)2(1)), unit cell of

Effect of selective substitution of 5-bromocytosine on conformation of DNA triple helices.

M Liu et al.

Journal of biomolecular structure & dynamics, 15(5), 895-903 (1998-06-10)

Three triplex DNAs containing 5-bromocytosine[BrC] were studied by vibrational spectroscopy and molecular modelling. Firstly, three oligodeoxypyrimidines of 5'-(TC)3-T4-(BrCT)3 [CBrC], 5'-(TBrC)3-T4-(CT)3 [BrCC] and 5'-(TBrC)3-T4-(BrCT)3 [BrCBrC] were synthesized and then reacted with an oligodeoxypurine of 5'-(AG)3 at pH=4.5 in phosphate buffer respectively

Influence of 5-bromodeoxycytosine substitution on triplex DNA stability and conformation.

L Yang et al.

Biophysical chemistry, 76(1), 25-34 (1999-02-24)

Three triple-helical hairpin DNAs with substitution of 5-bromocytosine for cytosine in different strands have been investigated by molecular mechanics and Raman spectroscopy. The stability of the three substituted triplexes were compared with the corresponding unsubstituted triplex DNA by the molecular

Facile formation of an intrastrand cross-link lesion between cytosine and guanine upon pyrex-filtered UV light irradiation of d((Br)CG) and duplex DNA containing 5-bromocytosine.

Yu Zeng et al.

Journal of the American Chemical Society, 126(21), 6552-6553 (2004-05-27)

Pyrex-filtered UV light irradiation of d(BrCG) and 5-bromocytosine-containing duplex DNA leads to facile formation of a cross-link lesion between the C5 carbon atom of cytosine and the C8 carbon atom of its adjacent guanine. A similar cross-link lesion has been

Epigenetics of chronic rhinosinusitis and the role of the eosinophil.

Kristin A Seiberling et al.

International forum of allergy & rhinology, 2(1), 80-84 (2012-02-09)

One theory for the pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP) involves aberration in the expression of genes that maintain the sinonasal innate immune system. We propose that the alteration in gene expression seen in CRSwNP is a result

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