由来生物
rabbit
品質水準
結合体
unconjugated
抗体製品の状態
IgG fraction of antiserum
抗体製品タイプ
primary antibodies
クローン
polyclonal
形状
buffered aqueous solution
分子量
57 kDa
化学種の反応性
rabbit, mouse, bovine, rat, guinea pig, human
濃度
0.5 mg - 1 mg/mL
テクニック
western blot: suitable
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
保管温度
−20°C
遺伝子情報
human ... CREB3L1(90993)
詳細
CREB3L1 (OASIS) is a transcription factor that is involved in the regulation of endoplasmic reticulum (ER) stress. It activates extracellular matrix gene expression and may play a role in the development of pancreas. CREB3L1 modulates the expression of the vasopressin gene in the hypothalamus of rats. EWSR1-CREB3L1 fusion transcript has been implicated in small cell osteosarcoma.
Rabbit Anti-CREB3L1 antibody recognizes bovine, human, mouse, rat, and canine CREB3L1.
Rabbit Anti-CREB3L1 antibody recognizes bovine, human, mouse, rat, and canine CREB3L1.
免疫原
Synthetic peptide directed towards the N terminal region of human CREB3L1
アプリケーション
Rabbit Anti-CREB3L1 antibody is suitable for western blot applications at a concentration of 1.25 μg/ml.
生物化学的／生理学的作用
The CREB3L1 gene encodes a protein with a transmembrane domain that is a transcriptional activator of the CREB/ATF family.
シーケンス
Synthetic peptide located within the following region: MDAVLEPFPADRLFPGSSFLDLGDLNESDFLNNAHFPEHLDHFTENMEDF
物理的形状
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
WGK 1
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
AV39769-100UG:
AV39769-100UL:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Ravi N Vellanki et al.
Endocrinology, 151(9), 4146-4157 (2010-07-30)
Old astrocyte specifically induced substance (OASIS) has previously been shown to be a putative endoplasmic reticulum (ER) stress sensor in astrocytes with a mechanism of activation that is similar to ATF6. In this study we investigated the expression and activation
Larisa V Debelenko et al.
Genes, chromosomes & cancer, 50(12), 1054-1062 (2011-10-12)
Cellular morphology of small cell osteosarcoma, an aggressive variant of osteosarcoma, is similar to Ewing sarcoma, but its molecular pathogenesis is largely unknown. We report the case of a 12-year-old girl with multifocal small cell osteosarcoma positive for the Ewing
Yan Fan et al.
The Journal of biological chemistry, 291(43), 22819-22829 (2016-09-10)
HIV-1 Tat is a major culprit for HIV/neuroAIDS. One of the consistent hallmarks of HIV/neuroAIDS is reactive astrocytes or astrocytosis, characterized by increased cytoplasmic accumulation of the intermediate filament glial fibrillary acidic protein (GFAP). We have shown that that Tat
Mingkwan Greenwood et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(11), 3810-3820 (2014-03-14)
Arginine vasopressin (AVP) is a neurohypophysial hormone regulating hydromineral homeostasis. Here we show that the mRNA encoding cAMP responsive element-binding protein-3 like-1 (CREB3L1), a transcription factor of the CREB/activating transcription factor (ATF) family, increases in expression in parallel with AVP
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