AV32623

抗HIC1抗体 ウサギ宿主抗体

affinity isolated antibody

• 別名: Anti-Hypermethylated in cancer 1
• UNSPSCコード: 12352203
• NACRES: NA.43

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 分子量: 74 kDa
• 化学種の反応性: human
• 濃度: 0.5 mg - 1 mg/mL
• テクニック: western blot: suitable
• NCBIアクセッション番号: NP_001091672
• UniProtアクセッション番号: Q14526-2
• 輸送温度: wet ice
• 保管温度: −20°C
• 遺伝子情報: human ... HIC1(3090)

詳細

詳細

HIC1 is a tumor suppressor that interacts with SIRT1 to regulate p53-depenedent responses to DNA damage.
Rabbit Anti-HIC1 antibody recognizes human, mouse, and rat HIC1.

免疫原

Synthetic peptide directed towards the N terminal region of human HIC1

アプリケーション

Rabbit Anti-HIC1 antibody can be used for western blot applications at a concentration of 0.25μg/ml.

生物化学的／生理学的作用

HIon Channel1 is a transcriptional repressor. HIon Channel1 may act as a tumor suppressor. HIon Channel1 may be involved in development of head, face, limbs and ventral body wall. Defects in HIon Channel1 may be a cause of the facial dysmorphism and additional birth defects (except for lissencephaly) seen in the contiguous gene disorder Miller-Dieker syndrome (MDS), like defective development of the nose, jaws, extremities, gastrointestinal tract, and kidney.

シーケンス

Synthetic peptide located within the following region: ALCASERRCSPLCGLDLSKKSPPGSAAPERPLAERELPPRPDSPPSAGPA

物理的形状

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable