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About This Item
実験式（ヒル表記法）:
C7H16NO5P
CAS番号:
分子量:
225.18
MDL番号:
UNSPSCコード:
12352200
PubChem Substance ID:
アッセイ
~95%
SMILES記法
NC(CCCCCP(O)(O)=O)C(O)=O
InChI
1S/C7H16NO5P/c8-6(7(9)10)4-2-1-3-5-14(11,12)13/h6H,1-5,8H2,(H,9,10)(H2,11,12,13)
InChI Key
MYDMWESTDPJANS-UHFFFAOYSA-N
遺伝子情報
human ... GRIN1(2902) , GRIN2A(2903) , GRIN2B(2904) , GRIN2C(2905) , GRIN2D(2906) , GRINA(2907)
rat ... Grin2a(24409) , Grin2b(24410)
生物化学的／生理学的作用
Selective NMDA glutamate receptor antagonist; anticonvulsant.
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
個人用保護具 (PPE)
Eyeshields, Gloves, type N95 (US)
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
M K Bazil et al.
The American journal of physiology, 260(1 Pt 2), H267-H275 (1991-01-01)
These studies investigated the role of spinal N-methyl-D-aspartic acid (NMDA) receptors in the mediation of cardiovascular responses evoked by L-glutamate (L-Glu) stimulation of the rostral ventrolateral medulla (RVM). Microinjections of L-Glu into the RVM of urethan-anesthetized rats increased mean arterial
Luiz F S Souza-Pinto et al.
Pharmacology, biochemistry, and behavior, 87(2), 250-257 (2007-06-01)
It is well established that the most persistent sign of withdrawal from chronic benzodiazepine use in humans is anxiety. In contrast to other types of drugs of abuse, the emergence of this anxiety does not seem to be linked directly
M Benveniste et al.
British journal of pharmacology, 104(1), 207-221 (1991-09-01)
1. The kinetics of action of 17 structurally related NMDA receptor competitive antagonists were measured under voltage clamp in mouse hippocampal neurones. Analysis of the response to rapid changes in antagonist concentration during constant application of agonist was used to
Ariandra G Sartim et al.
Behavioural pharmacology, 30(1), 59-66 (2018-10-10)
The transient receptor potential vanilloid 1 (TRPV1) can modulate stress-related behaviours, thus representing an interesting target for new antidepressant drugs. TRPV1 can trigger glutamate release and nitric oxide synthesis in the brain, mechanisms also involved in the neurobiology of depression.
Eric C Gustafson et al.
Journal of neurophysiology, 98(1), 122-130 (2007-05-18)
We have combined electrophysiology and chemical separation and measurement techniques with capillary electrophoresis (CE) to evaluate the role of endogenous d-serine as an NMDA receptor (NMDAR) coagonist in the salamander retina. Electrophysiological experiments were carried out using whole cell recordings
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