A3097

[Pro¹⁸, Asp²¹]-Amyloid β Protein Fragment 17-21 trifluoroacetate salt

≥98% (HPLC), solid

• 実験式（ヒル表記法）: C₃₃H₄₃N₅O₈
• CAS番号: 182912-74-9
• 分子量: 637.72
• UNSPSC Code: 12352200
• MDL number: MFCD01862668

特性

• assay: ≥98% (HPLC)
• form: solid
• UniProt accession no.: P05067
• storage temp.: −20°C
• SMILES string: CC(C)C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](CC(O)=O)C(O)=O
• Gene Information: human ... APP(351)

詳細

Biochem/physiol Actions

Inhibits amyloid formation in vitro and amyloid neurotoxicity in cell culture, reduces in vivo cerebral amyloid deposition and blocks amyloid fibrial formation in rat brain.

Inhibits amyloid formation in vitro, prevents amyloid neurotoxicity in cell culture, reduces in vivo cerebral amyloid deposition and completely blocks amyloid fibrial formation in rat brain.