3017
Transcreener® EPIGEN Methyltransferase Assay
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| あなたへ/カタログ番号 | 在庫状況 | 単価 |
|---|---|---|
1 ea | カートの在庫状況を確認する | ￥217,000 |
この商品について
NACRES:
NA.84
UNSPSC Code:
41122100
Storage temp.:
−20°C
Shipped in:
dry ice
￥217,000
カートの在庫状況を確認する
高品質はそのまま、さらにお手頃な価格になりました
shipped in
dry ice
storage temp.
−20°C
General description
The Transcreener® EPIGEN Methyltransferase Assay is a universal biochemical HTS assay for enzymes that produce S-adenosylhomocysteine (SAH), including all enzymes within the histone (HMTs) and DNA (DNMTs) methyltransferase families. It combines the extensively validated Transcreener® AMP2/GMP2 Assay, which relies on fluorescent immunodetection of AMP, with coupling enzymes that convert SAH to AMP. Enzyme activity is signaled by a decrease in fluorescence polarization as the bound tracer is displaced from the Transcreener® AMP2/GMP2 Antibody. The assay is a simple mix-and-read format with two liquid addition steps. Methyltransferase (MT) enzyme reactions are first quenched with Stop Buffer and then the SAH Detection Mixture containing coupling enzymes, Transcreener® AMP2/GMP2 antibody, and tracer is added. The assay provides excellent signal at low substrate conversion, with a Z′ =0.7 and =100 millipolarization shift (mP) under normal reaction conditions.
View full Transcreener® product list
View full Transcreener® product list
Physical form
Kit with buffered aqueous solutions
Preparation Note
3017-1K = 1,000 assay, 384-well
3017-10K = 10,000 assay, 384-well
3017-10K = 10,000 assay, 384-well
Legal Information
Transcreener is a registered trademark of BellBrook Labs
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当該品目 | |||
|---|---|---|---|
| shipped in dry ice | shipped in dry ice | shipped in dry ice | shipped in dry ice |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
