26740

コレステロール

from lanolin, ≥95.0% (GC)

• 別名: 3β-ヒドロキシ-5-コレステン, 5-コレステン-3β-オール
• 実験式（ヒル表記法）: C₂₇H₄₆O
• CAS番号: 57-88-5
• 分子量: 386.65
• Beilstein: 1915888
• EC Number: 200-353-2
• MDL番号: MFCD00003646
• UNSPSCコード: 12352200
• eCl@ss: 39023139
• PubChem Substance ID: 57648186

特性

• 由来生物: lanolin
• アッセイ: ≥95.0% (GC)
• フォーム: powder with small lumps
• 光学活性: [α]20/D −36±2°, c = 2% in dioxane
• bp: 360 °C (lit.)
• mp: 147-149 °C (lit.); 147-150 °C
• 密度: 1.067 g/mL at 25 °C (lit.)
• 保管温度: 2-8°C
• SMILES記法: CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
• InChI: 1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1
• InChI Key: HVYWMOMLDIMFJA-DPAQBDIFSA-N
• 遺伝子情報: human ... POLA1(5422) , TOP2A(7153) ; rat ... Ar(24208) , Polb(29240)

詳細

アプリケーション

Cholesterol was used to prepare immune-stimulating complexes to enhance cellular and humoral responses. It was incorporated in animal feed to study the effect of cholesterol-rich diet.

生物化学的／生理学的作用

すべての生体膜の主成分。脳脂質全体の約25%はコレステロ-ルです。

Cholesterol is a lipid makes up about 20-25% of the structural components of the cell membranes. It determines the fluidity and permeability of the membrane, making it permeable to water but not to ions and protons. Cholesterol also regulates the functions of the transporters and signaling proteins present on the plasma membrane. The major sites of cholesterol synthesis are small intestine and liver.

安全性情報

• 保管分類コード: 13 - Non Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)