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Merck

44577

Sigma-Aldrich

ドキシサイクリン ハイクレート

≥98.0% (TLC)

別名:

ドキシサイクリンヒドロクロリドヘミエタノラート半水和物

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About This Item

実験式(ヒル表記法):
C22H24N2O8 · HCl · 0.5H2O · 0.5C2H6O
CAS番号:
分子量:
512.94
Beilstein:
5702728
MDL番号:
UNSPSCコード:
51101500
PubChem Substance ID:

現在、価格および在庫状況を閲覧できません。

由来生物

synthetic

アッセイ

≥98.0% (TLC)

フォーム

powder

不純物

≤5% water
≤7% ethanol

faintly yellow to yellow

溶解性

H2O: 50 mg/mL, clear, yellow-green

抗生物質活性スペクトル

Gram-negative bacteria
Gram-positive bacteria
mycoplasma
parasites

作用機序

protein synthesis | interferes

SMILES記法

Cl[H].Cl[H].[H]O[H].CCO.C[C@@H]1C2[C@H](O)C3[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]3(O)C(O)=C2C(=O)c4c(O)cccc14.C[C@@H]5C6[C@H](O)C7[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]7(O)C(O)=C6C(=O)c8c(O)cccc58

InChI

1S/2C22H24N2O8.C2H6O.2ClH.H2O/c2*1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;1-2-3;;;/h2*4-7,10,14-15,17,25,27-29,32H,1-3H3,(H2,23,31);3H,2H2,1H3;2*1H;1H2/t2*7-,10?,14?,15-,17-,22-;;;;/m00..../s1

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詳細

Chemical structure: tetracycline

生物化学的/生理学的作用

作用機序:ドキシサイクリン塩酸塩は、ライム病スピロヘータBorrelia burgdorferiに対する炎症応答を阻害します。

活性スペクトル:in vivoにおけるマトリックスメタロプロテイナーゼの広域スペクトル阻害剤に対して有効です。

その他情報

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.
This product has been replaced by D9891-SIGMA | Doxycycline hyclate ≥98% (TLC)

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Lot/Batch Number

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

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  5. Is doxycycline hyclate soluble in DMSO?

    According to literature sources, doxycycline hyclate is soluble in DMSO at a concentration of 100 mM.

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