ABT336

Anti-BCAR3 Antibody

from rabbit, purified by affinity chromatography

• 別名: Breast cancer anti-estrogen resistance 3, NSP2, SH2D3B, Novel SH2-containing protein 2, SH2 domain-containing protein 3B, BCAR
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 精製方法: affinity chromatography
• 化学種の反応性: mouse
• 化学種の反応性（ホモロジーによる予測）: human (immunogen homology)
• テクニック: western blot: suitable
• UniProtアクセッション番号: O75815
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... BCAR3(8412)

詳細

詳細

Breast cancer anti-estrogen resistance protein 3 (BCAR3), also known as Novel SH2-containing protein 2 (NSP2) and SH2 domain-containing protein 3B (SH2D3B) is an adapter protein that regulates the proliferation in breast cancer cells. BCAR3 may also be regulated by cellular adhesion to extracellular matrix proteins. BCAR3 is found in several cancer cell lines; however, it is not found in nonmalignant breast tissue. When BCAR3 is overexpressed, it confers anti-estrogen resistance in breast cancer cell lines.

免疫原

KLH-conjugated linear peptide corresponding to human BCAR3.

アプリケーション

Research Category
アポトーシス及び癌

Anti-BCAR3 Antibody is a highly specific rabbit polyclonal antibody, that targets Breast cancer Anti-estrogen resistance protein 3 & has been tested in western blotting.

品質

Evaluated by Western Blotting in mouse kidney tissue lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected BCAR3 in 15 µg of mouse kidney tissue lysate.

ターゲットの説明

~104 kDa observed

物理的形状

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.

アナリシスノート

Control
Mouse kidney tissue lysate

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable