由来生物
rabbit
抗体製品の状態
purified antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
交差性
human, mouse
テクニック
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
UniProtアクセッション番号
輸送温度
dry ice
遺伝子情報
human ... PGK1(5230)
詳細
Phosphoglycerate kinase 1 (PGK1) and encoded by the gene names Pgk1 or Pgk-1, is important for phosphoprotein glycolysis. PGK1 is an ATP-generating glycolytic enzyme that forms part of the glycolytic pathway that is often highly expressed in prostate cancer and is regulated by hypoxia-inducible factor-1α. Extracellular PGK1 facilitates the cleavage of plasminogen generating the vascular inhibitor angiostatin.
免疫原
Epitope: Central region
KLH-conjugated synthetic peptide corresponding to the central region of human PGK1.
アプリケーション
Research Category
代謝
代謝
Research Sub Category
グルコース/グリコーゲン代謝
グルコース/グリコーゲン代謝
Detect PGK1 using this rabbit polyclonal Anti-PGK1 Antibody, Cat. No. ABS787, validated for use in Western Blotting, Immunohistochemistry, Immunocytochemistry, and Flow Cytometry.
Western Blotting Analysis (WB): A 1:1000 dilution from a representative lot of this antibody detected PGK1 in multiple lysates. See chart for reactivity detail.
Immunohistochemistry Analysis (IHC): A 1:10-50 dilution from a representative lot detected PGK1 in human cancer tissue.
Immunocytochemistry Analysis (ICC): A 1:10-50 dilution from a representative lot detected PGK1 in HeLa cells.
Flow Cytometry (FC): A 1:10-50 dilution of this antibody detected PGK1 in HeLa cells.
Immunohistochemistry Analysis (IHC): A 1:10-50 dilution from a representative lot detected PGK1 in human cancer tissue.
Immunocytochemistry Analysis (ICC): A 1:10-50 dilution from a representative lot detected PGK1 in HeLa cells.
Flow Cytometry (FC): A 1:10-50 dilution of this antibody detected PGK1 in HeLa cells.
品質
Evaluated by Western Blotting in HT1376 cell lysate.
Western Blotting Analysis (WB): A 1:1000 dilution of this antibody detected PGK1 in HT1376 cell lysate.
Western Blotting Analysis (WB): A 1:1000 dilution of this antibody detected PGK1 in HT1376 cell lysate.
ターゲットの説明
~48 kDa observed. Uncharacterized bands may be observed in some lysate(s).
物理的形状
Ammonium Sulfate
Format: Purified
Purified rabbit polyclonal in buffer containing PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
保管および安定性
Stable for 1 year at 2-8°C from date of receipt.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
その他情報
Concentration: Please refer to lot specific datasheet.
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Penelope J Boyd et al.
PLoS genetics, 13(4), e1006744-e1006744 (2017-04-21)
Degeneration and loss of lower motor neurons is the major pathological hallmark of spinal muscular atrophy (SMA), resulting from low levels of ubiquitously-expressed survival motor neuron (SMN) protein. One remarkable, yet unresolved, feature of SMA is that not all motor
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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