ABS456

Anti-WNT10A Antibody

from rabbit, purified by affinity chromatography

• 別名: Protein Wnt-10a, Wingless-type MMTV integration site family 10a
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rabbit
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 精製方法: affinity chromatography
• 化学種の反応性: mouse, human
• テクニック: immunofluorescence: suitable; immunohistochemistry: suitable (paraffin); western blot: suitable
• UniProtアクセッション番号: Q9GZT5
• 輸送温度: wet ice
• 遺伝子情報: human ... WNT10A(80326)

詳細

詳細

Wingless-type MMTV integration site family 10a (WNT10A) plays crucial role in normal development such as regulation of cell fate, patterning during embryogenesis and neoplastic transformation. Elevated levels of WNT10A have been detected in several human tumors and cancer cell lines including colorectal cancer and chronic lymphocytic leukemia. This evidence suggests that uncontrolled Wnt signaling may contribute to the abnormal apoptosis that characterizes these malignancies. Defects in WNT10A have been shown to be related and possibly are the cause of ectodermal dysplasia anhidrotic (EDA), also known ectodermal dysplasia hypohidrotic autosomal recessive (HED). Other recent evidence had suggested that mutation in WNT10A is associated with odonto-onycho-dermal dysplasia (OODD), an autosomal recessive ectodermal dysplasia and Schopf-Schulz-Passarge syndrome (SSPS).

免疫原

KLH-conjugated linear peptide corresponding to human WNT10A.

アプリケーション

Research Category
細胞シグナル伝達

Research Sub Category
発生シグナル伝達

Anti-WNT10A Antibody is a highly specific rabbit polyclonal antibody, that targets Wnt & has been tested in western blotting, IHC (Paraffin) & Immunofluorescence.

Immunohistochemistry Analysis: 10 µg/mL from a representative lot detected WNT10A in human skeletal muscle tissue.

Immunofluorescence Analysis: 20 μg/mL from a representative lot detected WNT10A in human skeletal muscle cells.

品質

Evaluated by Western Blotting in RAW264.7 cell lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected WNT10A in 15 µg of RAW264.7 cell lysate.

ターゲットの説明

~46 kDa observed. Uncharacterized bands may appear in some lysate(s).

物理的形状

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.

アナリシスノート

Control
RAW264.7 cell lysate

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable