おすすめの製品
由来生物
rabbit
品質水準
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
精製方法
affinity chromatography
化学種の反応性
human, mouse
テクニック
immunohistochemistry: suitable (tissue)
western blot: suitable
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... SOX11(6664)
詳細
SRY box-containing 11 (Sox11) is a neural transcription factor belonging to the DNA-binding high-mobility group (HMG) box protein super family. It is highly expressed during embryonic development and regulates genes involved in neurite growth and survival. Sox11 plays an important role in the formation of sensory neurons and organogenesis. Sox11-deficient mice show defects in multiple organs including the lung, heart, and pancreas. Sox11 also plays a critical role as a tumor suppressor. Epigenetic suppression of the Sox11 gene, primarily through promoter hypermethylation, contributes to various forms of neoplasms. In adults, Sox11 may be involved in the regeneration of neurons after nerve injury by inducing the expression of the small proline rich protein 1a gene (Sprr1a).
免疫原
KLH-conjugated linear peptide corresponding to human Sox-11.
アプリケーション
Research Category
ニューロサイエンス
ニューロサイエンス
Research Sub Category
ニューロン発生
ニューロン発生
Anti-Sox11 Antibody detects level of Sox11 & has been published & validated for use in 0.
Immunohistochemistry: A 1:1,000 dilution from a representative lot detected Sox-11 in normal mouse hippocampus and cerebellum tissues.
Western Blot Analysis: A representative lot detecte Sox-11 in human brain tissue lysate.
Western Blot Analysis: A representative lot detecte Sox-11 in human brain tissue lysate.
品質
Evaluated by Western Blot in mouse brain tissue lysate.
Western Blot Analysis: 0.5 mg/mL of this antibody detected Sox-11 in 10 mg of mouse brain tissue lysate.
Western Blot Analysis: 0.5 mg/mL of this antibody detected Sox-11 in 10 mg of mouse brain tissue lysate.
ターゲットの説明
~57 kDa observed
物理的形状
Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
保管および安定性
Stable for 1 year at 2-8°C from date of receipt.
アナリシスノート
Control
Mouse brain tissue lysate
Mouse brain tissue lysate
その他情報
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
12 - Non Combustible Liquids
WGK
WGK 1
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
ABN105:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Yuyan Cheng et al.
Nature communications, 13(1), 4418-4418 (2022-07-30)
The inability of neurons to regenerate long axons within the CNS is a major impediment to improving outcome after spinal cord injury, stroke, and other CNS insults. Recent advances have uncovered an intrinsic program that involves coordinate regulation by multiple
Elena Spina et al.
Nature communications, 13(1), 1421-1421 (2022-03-19)
Gpr125 is an orphan G-protein coupled receptor, with homology to cell adhesion and axonal guidance factors, that is implicated in planar polarity and control of cell movements. By lineage tracing we demonstrate that Gpr125 is a highly specific marker of
Rotem Ben-Tov Perry et al.
Cell reports, 42(10), 113168-113168 (2023-09-24)
Long noncoding RNAs (lncRNAs) are expressed in many brain circuits and types of neurons; nevertheless, their functional significance for normal brain functions remains elusive. Here, we study the functions in the central nervous system of Silc1, an lncRNA we have
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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