ABE211

Anti-CFP1 Antibody

serum, from rabbit

• 別名: CXXC finger 1 (PHD domain), PHD finger and CXXC domain-containing protein 1, CXXC-type zinc finger protein 1, cpG-binding protein, CpG binding protein, zinc finger, CpG binding-type containing 1, DNA-binding protein with PHD finger and CXXC domain
• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Conjugate: unconjugated
• Clone: polyclonal
• Application: WB
• Citations: 3

特性

• biological source: rabbit
• conjugate: unconjugated
• antibody form: serum
• antibody product type: primary antibodies
• clone: polyclonal
• species reactivity: human, rat
• technique(s): western blot: suitable
• NCBI accession no.: NP_055408
• UniProt accession no.: Q9P0U4
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... CXXC1(30827)

詳細

General description

CXXC finger protein 1 (CFP1) is part of the Setd1A and Setd1B methyltransferase compounds. Research shows that CFP1 also interacts with the cytosine methylation mechanism. CFP1 is necessary for development of mammals and is a key regulator of chromatin structure. Embryonic stem cells that are missing CFP1 are more susceptible to DNA-damaging agents and tend to build up more DNA damage. CFP1 has been shown to also be a regulator of DNA repair.

~78 kDa observed. A cross-reacting band observed at ~110 kDa

Immunogen

GST-tagged recombinant protein corresponding to human CFP1.

Application

Use Anti-CFP1 Antibody (Rabbit Polyclonal Antibody) validated in WB to detect CFP1 also known as CXXC finger 1 (PHD domain), cpG-binding protein.

Analysis Note

Evaluated by Western Blot in HeLa nuclear extract.

Western Blot Analysis: 1:1,000 dilution of this antibody detected CFP1 on 10 µg of HeLa nuclear extract.

安全性情報

• 保管分類: 10 - Combustible liquids
• wgk: WGK 1