由来生物
rabbit
品質水準
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
精製方法
affinity chromatography
交差性
mouse, human, rat
交差性（ホモロジーによる予測）
chimpanzee (based on 100% sequence homology)
テクニック
immunohistochemistry: suitable
western blot: suitable
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... YY1AP1(55249)
詳細
YY1-associated protein 1 (YY1AP1), also known as Hepatocellular carcinoma susceptibility protein, Hepatocellular carcinoma-associated protein 2, is encoded by the gene name YY1AP1, HCCA2, and YY1AP. YY1AP1 has been demonstrated to enhance transcription activation by interacting with YY1. Recent studies have shown that YY1AP1 may play a role in cell cycle regulation. YY1AP1 interacts with YY1 and MAD2L2. YY1AP1 is expressed ubiquitously. YY1AP1 has been detected in small intestine, skeletal muscle, lung, pancreas, brain, stomach, spleen, colon and heart. At very low levels, YY1AP1 has been detected in healthy liver. YY1AP1 is highly expressed in most liver carcinomas.
免疫原
Epitope: Near N-terminal
KLH-conjugated linear peptide corresponding to human YY1AP1 near the N-terminal.
アプリケーション
Research Category
アポトーシス及び癌
アポトーシス及び癌
Research Sub Category
アポトーシス-追加
アポトーシス-追加
This Anti-YY1AP1 antibody is validated for use in WB, IH for the detection of YY1AP1.
Western Blotting Analysis: 0.5 µg/mL from a representative lot detected YY1AP1 in 10 µg of C2C12, Hek293, HeLa, HepG2, human placenta, Huvec, Jurkat, L6, mouse brain, NIH-3T3, PC12, PC3, and Raw 264.7 lysate.
Immunohistochemistry Analysis: A 1:50-250 dilution from a representative lot detected YY1AP1 in human cerebellum, mouse hindbrain, and mouse cerebellum tissue.
Immunohistochemistry Analysis: A 1:50-250 dilution from a representative lot detected YY1AP1 in human cerebellum, mouse hindbrain, and mouse cerebellum tissue.
品質
Evaluated by Western Blotting in A431 cell lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected YY1AP1 in 10 µg of A431 cell lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected YY1AP1 in 10 µg of A431 cell lysate.
ターゲットの説明
~90 kDa observed. The endogenous YY1AP protein signal is found at 90 kDa, in agreement with the predicted protein size of 750 amino acids derived from open reading frame (Wang, C.Y., et al. (2004). J. Biol. Chem. 279:17750-17755).
物理的形状
Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
保管および安定性
Stable for 1 year at 2-8°C from date of receipt.
その他情報
Concentration: Please refer to lot specific datasheet.
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
12 - Non Combustible Liquids
WGK
WGK 1
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
ABC477:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Dong-Chuan Guo et al.
American journal of human genetics, 100(1), 21-30 (2016-12-13)
Fibromuscular dysplasia (FMD) is a heterogeneous group of non-atherosclerotic and non-inflammatory arterial diseases that primarily involves the renal and cerebrovascular arteries. Grange syndrome is an autosomal-recessive condition characterized by severe and early-onset vascular disease similar to FMD and variable penetrance
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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