ABC327

Anti-PD-L2 Antibody

from rabbit, purified by affinity chromatography

• 別名: Programmed cell death 1 ligand 2, PD-1 ligand 2, PD-L2, PDCD1 ligand 2, Programmed death ligand 2, Butyrophilin B7-DC, B7-DC, CD273
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 精製方法: affinity chromatography
• 化学種の反応性: human, mouse
• テクニック: immunofluorescence: suitable; immunohistochemistry: suitable (paraffin); western blot: suitable
• UniProtアクセッション番号: Q9BQ51
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... PDCD1LG2(80380)

詳細

詳細

Programmed cell death ligand 2 (PD-L2, PD-1 ligand 2, PDCD1 ligand 2), also known as Butyrophilin B7-DC (B7-DC), is a member of the BTN/MOG family and immunoglobulin superfamily which is thought to act as a negative regulator of T cell activation. PD-L2 may play a role in stimulating an immunogenic response through an alternative receptor from PD-1. PD-L2 is highly expressed in heart, placenta, pancreas, lung, and liver and weakly expressed in spleen, lymph nodes, and thymus.

特異性

This antibody only recognizes the largest isoform at ~31 kDa.

免疫原

KLH-conjugated linear peptide corresponding to human PD-L2.

アプリケーション

Research Category
アポトーシス及び癌

Research Sub Category
アポトーシス-追加

Anti-PD-L2 Antibody is a highly specific rabbit polyclonal antibody, that targets Programmed cell death 1 ligand 1 & has been tested in western blotting, IHC (Paraffin) & Immunofluorescence.

Immunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected PD-L2 in mouse brain tissue.

Immunofluorescence Analysis: 20 μg/mL from a representative lot detected PD-L2 in mouse brain cells.

品質

Evaluated by Western Blotting in Raji cell lysate

Western Blotting Analysis: 2 µg/mL of this antibody detected PD-L2 in 15 µg of Raji cell lysate.

ターゲットの説明

~31 kDa observed. Uniprot describes 2 isoforms at ~21 kDa and one isoform at ~31 kDa Uncharacterized bands may appear in some lysate(s).

物理的形状

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.

アナリシスノート

Control
Raji cell lysate

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable