ABC148

Anti-TMEM132A Antibody

from rabbit, purified by affinity chromatography

• 別名: Transmembrane protein 132A, HSPA5-binding protein 1, TMEM132A
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 精製方法: affinity chromatography
• 交差性: human, rat, mouse
• テクニック: immunohistochemistry: suitable (paraffin); western blot: suitable
• NCBIアクセッション番号: NP_060340
• UniProtアクセッション番号: Q24JP5
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... TMEM132A(54972)

詳細

詳細

Transmembrane protein 132A (TMEM132A), or HSPA5-binding protein 1 (HSPA5BP1), is thought to be involved in embryonic and postnatal development of the brain, and the increased cell death resistance induced by serum starvation in cultured cells. TMEM132A is known to regulate cAMP-induced GFAP gene expression through phosphorylation of STAT3.

特異性

This antibody recognizes the cytoplasmic domain of TMEM132A.

免疫原

Epitope: Cytoplasmic domain

KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human TMEM132A.

アプリケーション

Research Category
アポトーシス及び癌

Research Sub Category
アポトーシス-追加

Detect TMEM132A using this rabbit polyclonal antibody, Anti-TMEM132A Antibody validated for use in western blotting & IHC (Paraffin).

Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected Neuro2A in human cerebellum and thalamus tissues.

品質

Evaluated by Western Bloting in Neuro2A cell lysate.

Western Blotting Analysis: 0.1 µg/mL of this antibody detected TMEM132A in 10 µg of Neuro2A cell lysate.

ターゲットの説明

~140 kDa observed. The calculated molecular weight of this protein is 110kDa This protein has been observed at ~135 and ~170 kDa due to glycosylation, myristoylation, and phosphorylation (Kentaro, O. H., et al. (2003). J Biol Chem. 278(12): 10531-10537.). Uncharacterized band(s) may be observed in some cell lysates.

物理的形状

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.

アナリシスノート

Control
Neuro2A cell lysate

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable