AB3749

Anti-mGCM1 Antibody

from rabbit, purified by affinity chromatography

• 別名: GCM motif protein 1, Glial cells missing homolog 1, chorion-specific transcription factor GCMa, glial cells missing homolog a
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 精製方法: affinity chromatography
• 化学種の反応性: human
• テクニック: western blot: suitable
• 入力: sample type pancreatic stem cell(s); sample type neural stem cell(s)
• UniProtアクセッション番号: P70348
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... GCM1(8521)

詳細

詳細

GCM1 is a DNA binding protein with a GCM motif (glial cell missing motif) that is a key transcription factor for determining the fate of stem cells within the nervous system, in addition to being critical for placental development. This protein binds to the GCM motif (A/G)CCCGCAT, a novel sequence among known targets of DNA binding proteins. The N-terminal DNA-binding domain confers the unique DNA binding activity of this protein. Current studies indicate that the introduction of the mouse GCM1 gene in cultured cells from embryonic brains resulted in the induction of an astrocyte lineage.

特異性

Comparison of sequence homology suggests that this antibody will also react in mouse and rat; however, reactivity to other species has not been tested.

This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptided selected from the C-terminal region mouse GCM1.

免疫原

Epitope: C-terminus

Synthetic GCM1 peptide, a.a. 401-418.

アプリケーション

Research Category
幹細胞研究

Research Sub Category
神経幹細胞

This Anti-mGCM1 Antibody is validated for use in WB for the detection of mGCM1.

品質

Routinely evaluated by western blot on HEK-293 lysates.

Western Blotting: Recommended working dilutions are 1:1000 – 1:2500.

ターゲットの説明

50 kDa

物理的形状

Peptide affinity purified

Purified rabbit polyclonal antibody in buffer containing PBS with 0.09% sodium azide.

保管および安定性

Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months. Avoid repeat freeze/thaw cycles.

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable