8.55016

Rink Amide PEGA resin

Novabiochem^®

• UNSPSCコード: 12352111

特性

• 品質水準: 200
• 製品種目: Novabiochem^®; PEGA
• フォーム: beads
• 反応適合性: reaction type: Fmoc solid-phase peptide synthesis
• メーカー／製品名: Novabiochem^®
• アプリケーション: peptide synthesis
• 官能基: amine
• 保管温度: 2-8°C

詳細

詳細

An excellent acid-labile support for the solid phase synthesis of peptide amides. This resin is prepared by derivatization of amino PEGA resin with the modified Rink linker. It is supplied without Fmoc protection of the linker benzhydrylamine group as this has been found to improve stability. Cleavage is effected with 95% TFA. PEGA-based resins are compatible with aqueous and alcoholic solvents, and are permeable to macromolecules up to 35 kD. For further information, please refer to the product entry for amino PEGA resin (855015). Note: PEGA resins are supplied swollen in ethanol, with 1g dry resin corresponding to approximately 15 mL of swollen resin. As the beads of PEGA resins become very sticky and easily damaged when shrunk or dried, they are best handled in a swollen state. To use, the appropriate amount of swollen resin should be weighed into a reaction vessel and any residual ethanol removed by copious washings with the appropriate solvent or solvent mixture. After peptide assembly, the resin should be washed with DCM and transferred to the cleavage vessel. Excess DCM can be removed under vacuum, and the shrunk resin treated with the TFA cocktail. The characteristics of the swollen resin, its robustness and high permeability enables its use in both batch and continuous flow synthesis apparatus.

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

関連事項

Replaces: 01-64-0101

アナリシスノート

Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.20 - 0.50 mmol/g
Swelling Volume (in DMF): lot specific result
dry resin %: lot specific result
The resin is sold swollen ethanol.

法的情報

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable