616430

TGF-α, Human, Recombinant, E. coli

• 別名: TGF-α, Human, Recombinant, E. coli, Transforming Growth Factor-α
• CAS番号: 105186-99-0
• MDL番号: MFCD00082077
• UNSPSCコード: 12352202

特性

• アッセイ: ≥97% (SDS-PAGE)
• 品質水準: 100
• フォーム: lyophilized
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze
• 不純物: ≤100 pg/μg Endotoxin (pg/μg TGF-α)
• 輸送温度: dry ice
• 保管温度: −70°C

詳細

詳細

Recombinant, human transforming growth factor-α expressed in E. coli. Plays an important role in cell-cell adhesion and cell growth and differentiation. Reported to play a role in the development of hormonal insensitivity in estrogen-receptor-positive breast cancers.

生物化学的／生理学的作用

ED₅₀= 0.1-0.4 ng/ml as measured by the ability to stimulate ³H-thymidine incorporation in the mouse fibroblast cell line Balb/3T3

警告

Toxicity: Standard Handling (A)

物理的形状

Lyophilized from 30% acetonitrile, 0.1% TFA.

再構成

Following reconstitution, aliquot and freeze (-70°C) for long-term storage or refrigerate (4°C) for short-term storage. Avoid freeze/thaw cycles of solutions. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -70°C.

Reconstitute to a concentration of ≥10 µg/ml with sterile 10 mM acetic acid containing ≥0.1% HSA or BSA.

その他情報

Nicholson, R.I., et al. 1994. Cancer Res. 54, 1684.
Anklesaria, P., et al. 1990. Proc. Natl. Acad. Sci. USA87, 3289.
Massague, J. 1990. J. Biol. Chem.265, 21393.
Watanabe, S., et al. 1987. Proc. Natl. Acad. Sci. USA84, 1258.
Schreiber, A.B., et al. 1986. Science232, 1250.
Tam, J.P. 1985. Science229, 673.
Derynck, R., et al. 1984. Cell38, 327.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany