219457

Cdk Inhibitor, p35 - CAS 471270-60-7 - Calbiochem

• 別名: Cdk Inhibitor, p35 - CAS 471270-60-7 - Calbiochem, 2-(3-Hydroxypropylamino)-6-( o-hydroxybenzylamino)-9-isopropylpurine
• 実験式（ヒル表記法）: C₁₈H₂₄N₆O₂
• CAS番号: 471270-60-7
• 分子量: 356.42
• UNSPSCコード: 12352200

特性

• アッセイ: ≥95% (HPLC)
• 品質水準: 100
• フォーム: solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; protect from light
• 色: yellow
• 溶解性: DMSO: 10 mg/mL
• 輸送温度: ambient
• 保管温度: −20°C

詳細

詳細

This product has been discontinued.

An analog of Olomoucine (Cat. No. 495620) that acts as a potent inhibitor of Cdk1 (IC₅₀ = 100 nM) and Cdk2 (IC₅₀ = 80 nM). Also displays anti-proliferative and pro-apoptotic effects. The correlation between inhibition of Cdk1/Cdk2 and inhibition of cell proliferation suggests that the anti-proliferative effects are due, in part, to Cdk inhibition.

An analog of Olomoucine (Cat. No. 495620) that acts as a potent inhibitor of Cdk1 (IC₅₀ = 100 nM) and Cdk2 (IC₅₀ = 80 nM). Also displays anti-proliferative and pro-apoptotic effects.

生物化学的／生理学的作用

Cell permeable: no

Primary Target
CDK1, CDK2

Product does not compete with ATP.

Reversible: no

Target IC₅₀: 100 nM, 80 nM, against Cdk1 and Cdk2, respectively

包装

Packaged under inert gas

警告

Toxicity: Standard Handling (A)

再構成

Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

その他情報

Vermeulen, K., et al. 2002. Leukemia16, 299.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 10-13 - German Storage Class 10 to 13