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Merck
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主要文書

安全性情報

09-823

Sigma-Aldrich

Anti-JMJD1A Antibody

from rabbit, purified by affinity chromatography

別名:

JMJD, lysine (K)-specific demethylase 3A, testis-specific protein A, jumonji domain containing 1A, jumonji C domain-containing histone demethylase 2A, jumonji domain containing 1, Jumonji domain-containing protein 1A, JmjC domain-containing histone demet

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About This Item

UNSPSCコード:
12352203
eCl@ss:
32160702
NACRES:
NA.41

由来生物

rabbit

品質水準

抗体製品の状態

affinity isolated antibody

抗体製品タイプ

primary antibodies

クローン

polyclonal

精製方法

affinity chromatography

交差性

human, mouse

テクニック

ChIP: suitable
immunoprecipitation (IP): suitable
western blot: suitable

NCBIアクセッション番号

UniProtアクセッション番号

輸送温度

wet ice

ターゲットの翻訳後修飾

unmodified

遺伝子情報

human ... KDM3A(55818)

詳細

JMJD1A (jumonji domain-containing 1a) is a histone demethylase that plays a key role in the histone code. Functionally, this protein is known to demethylate mono- and dimethylated histoneH3 at lysine 9, while demonstrating virtually no demethylation activity for trimethylated lysine 9 of histone H3. A product of the JHDM2A gene, this protein has been demonstrated to play a role in hypoxia, spermatogenesis, and cell differentiation with loss of function of JMJD1A resulting embryonic stem cell differentiation.

免疫原

GST-tagged recombinant protein corresponding to mouse JMJD1A.

アプリケーション

Research Category
エピジェネティクス及び核内機能分子
Research Sub Category
ヒストン修飾タンパク質
Immunoprecipitation Analysis: 5 µg of a representative lot of this antibody immunoprecipitated JMJD1A in HeLa nuclear extract.

Western Blot Analysis: A representitive lot of this antibody detected JMJD1A in mouse ESC chromatin extract.
Use Anti-JMJD1A Antibody (Rabbit Polyclonal Antibody) validated in WB, IP to detect JMJD1A also known as lysine (K)-specific demethylase 3A, testis-specific protein A.

品質

Evaluated by Western Blot in HEK293 nuclear extract.

Western Blot Analysis: 1 µg/mL of this antibody detected JMJD1A on 10 µg of HEK293 nuclear extract.

ターゲットの説明

~147 kDa observed.

物理的形状

Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.

アナリシスノート

Control
HEK293 nuclear extract.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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保管分類コード

12 - Non Combustible Liquids

WGK

WGK 1

引火点(°F)

Not applicable

引火点(℃)

Not applicable


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

09-823:


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Glauber R de S Araújo et al.
Methods in molecular biology (Clifton, N.J.), 2775, 141-153 (2024-05-17)
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Itze C Navarro-Hernandez et al.
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ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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