09-466

Anti-phospho-CrkL (Tyr207) Antibody

Upstate^®, from rabbit

• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: affinity purified immunoglobulin
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 精製方法: affinity chromatography
• 化学種の反応性: mouse, rat, human
• メーカー／製品名: Upstate^®
• テクニック: western blot: suitable
• NCBIアクセッション番号: NP_005198
• UniProtアクセッション番号: P46109
• 輸送温度: dry ice
• ターゲットの翻訳後修飾: phosphorylation (pTyr207)
• 遺伝子情報: human ... CRKL(1399)

詳細

詳細

CRKL belongs to a family of adaptor proteins containing SH2/SH3 domains that couple to effector proteins including p130CAS, SOS, Abl, and Arg. CRKL plays a role in the mediation of Integrin- and Rac-dependent cell migration and in Ras-dependent activation of JNK. The protein is also involved in T-cell activation. Phosphorylation of CrkL on Tyr207 is known to be correlated with its inhibition.

特異性

Recognizes CrkL only when phosphorylated on Tyr207.

免疫原

KLH synthetic peptide including and encompassing Tyr 207 of human CrkL.

アプリケーション

Research Category
細胞シグナル伝達

Research Sub Category
細胞骨格シグナル伝達

Detect phospho-CrkL (Tyr207) using this Anti-phospho-CrkL (Tyr207) Antibody validated for use in WB.

品質

Routinely evaluated by western blot on K563 cell lysates.

ターゲットの説明

39 kDa

物理的形状

Purified rabbit polyclonal IgG in storage buffer containing PBS with 0.05% sodium azide in 50% glycerol.

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.
Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

アナリシスノート

Control
K562

法的情報

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2