07-1521

Anti-phospho-NDRG3 (Ser331) Antibody

from rabbit, purified by affinity chromatography

• 別名: Protein NDRG3, Protein Ndr3
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rabbit
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 精製方法: affinity chromatography
• 化学種の反応性: horse, mouse
• 化学種の反応性（ホモロジーによる予測）: bovine (based on 100% sequence homology), equine (based on 100% sequence homology), rhesus macaque (based on 100% sequence homology), chimpanzee (based on 100% sequence homology), rat (based on 100% sequence homology), human (based on 100% sequence homology)
• テクニック: western blot: suitable
• NCBIアクセッション番号: NP_038893
• UniProtアクセッション番号: Q9QYF9
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: phosphorylation (pSer331)
• 遺伝子情報: bovine ... Ndrg3(514399) ; chimpanzee ... Ndrg3(735544) ; human ... NDRG3(57446) ; mouse ... Ndrg3(29812) ; rat ... Ndrg3(296318)

詳細

詳細

NDGR3 is a member of the N-myc down-regulated gene (NDGR) family which includes NDGR1-4. NDGR3 is ubiquitously expressed but is abundant in the brain, testis, prostate, and ovary. The precise role of NDGR3 has not been elucidated; however, previous studies have suggested that NDGR3 may play a role in spermatogenesis in mice, and aberrant expression of NDGR3 may lead to the proliferation of prostate cancer cells. NDGR3-mediated tumor growth may be due to upregulation of various angiogenic chemokines such as chemokine ligands 1, 3, and 5, which promote angiogenesis in tumors.

特異性

This antibody recognizes NDRG3 phosphorylated at (Ser331).

免疫原

Epitope: Phosphorylated (Ser331)

KLH-conjugated linear peptide corresponding to mouse NDRG3 phosphorylated at (Ser331).

アプリケーション

Research Category
細胞シグナル伝達

Research Sub Category
発生シグナル伝達

Detect phospho-NDRG3 (Ser331) using this Anti-phospho-NDRG3 (Ser331) Antibody validated for use in Western Blotting.

品質

Evaluated by Western Blot in mouse embryonic fibroblast cell lysates under multiple conditions (see image).

Western Blot Analysis: 0.1 µg/mL of this antibody detected NDRG3 on 10 µg of mouse embryonic fibroblast cell lysates under multiple conditions (see image).

ターゲットの説明

~33 kDa observed

物理的形状

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.

アナリシスノート

Control
Mouse embryonic fibroblast cell lysates under multiple conditions (see image).

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable