フォーム
liquid
メーカー／製品名
Avanti Research™ - A Croda Brand 330654
包装
1 ea of 1 × (ELISA strip packaged in foil pouch)
輸送温度
wet ice
保管温度
2-8°C
詳細
Avanti Lipid Snoopers™ comprise lipid spotted on solid support and are stable and aid highly sensitive semi-quantitative measurements for lipid detection. Ganglioside GM3 (monosialodihexosylganglioside) are glycosphingolipids (GSLs) which are membrane-bound comprising of a sialic acid residue and an oligosaccharide head structure. It is present in milk and in kidney cells.
ELISA Snoopers™ are 8-well strips pre-coated with a single high-quality lipid species. They can be used to investigate protein-lipid interactions, and characterize and titrate lipid binding proteins. This format provides the following advantages:
The 8-well strips are available in optically clear, white, or black surfaces for use in colormetric, luminescent and fluorescent assays, respectively. Avanti Lipid Snoopers ELISA Strips allow multiple sample conditions to be probed simultaneously in a single plate making them a perfect complement to Avanti Lipid Snoopers Nitrocellulose Strips.
- quantitative lipid-protein binding studies
- assemble a 96-well plate using only the lipids of interest for binding studies
- flexibility - use 8 to 96 wells, and 1 to 12 lipids as needed.
The 8-well strips are available in optically clear, white, or black surfaces for use in colormetric, luminescent and fluorescent assays, respectively. Avanti Lipid Snoopers ELISA Strips allow multiple sample conditions to be probed simultaneously in a single plate making them a perfect complement to Avanti Lipid Snoopers Nitrocellulose Strips.
生物化学的／生理学的作用
Low levels of ganglioside GM3 is implicated in the pathogenesis of rheumatoid arthritis. It modulates immunological functions by inhibiting cytokine production. High GM3 levels are also correlated to the nephrotic syndrome and diabetic nephropathy. Avanti Lipid Snoopers™ aid in probing protein–lipid interaction by chemiluminescent detection method. Snoopers™ strips are useful in characterizing lipid-binding antibodies and decoding cell signalling pathways.
包装
ELISA Strip Packaged in Foil Pouch (330654-1EA)
法的情報
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Snoopers is a trademark of Avanti Polar Lipids, LLC
保管分類コード
12 - Non Combustible Liquids
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
330654-1EA:
330654-VAR:
最新バージョンのいずれかを選択してください：
The missing link-likely pathogenetic role of GM3 and other gangliosides in the development of diabetic nephropathy
Vukovic I, et al.
Kidney & Blood Pressure Research, 40(3), 306-314 (2015)
Ganglioside biochemistry
Kolter, Thomas
ISRN Biochemistry, 2012 (2012)
Ganglioside GM3 has an essential role in the pathogenesis and progression of rheumatoid arthritis
Tsukuda Y, et al.
Testing, 7(6) (2012)
Ganglioside GM3 has an essential role in the pathogenesis and progression of rheumatoid arthritis
Tsukuda Y, et al.
PLoS ONE, 7(6) (2012)
Avanti lipid tools: connecting lipids, technology, and cell biology
Sims KH, et al.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1841(8), 1038-1048 (2014)
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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