CDPG-502

Cationic PEGylated Liposomes

DOPC:Chol:DOTAP:DOPE-PEG(2000) (55:30:10:5 molar ratio 10mM)

• UNSPSCコード: 12352211
• NACRES: NA.25

特性

• 品質水準: 100
• 組成: Phosphate buffered saline
• 濃度: 10 mM
• 不純物: 10 mol % DOTAP; 30 mol % Cholesterol ; 5 mol % DOPE-PEG2000; 55 mol % DOPC
• 粒径: 100 nm
• pH: 7.4

詳細

詳細

Poly(ethylene glycol) (PEG) is commonly added to liposomes to improve stability, hydrophilicity and enhance circulation time. Anionic PEGylated liposomes protect liposomes from circulating proteins, improving their plasma clearance and enhancing their therapeutic effects. In addition, anionic liposomes demonstrate greater stability in solution, lead to lower aggregation when compared to neutral liposomes, and have increased endocytosis when compared with cationic and neutral liposomes.

アプリケーション

Drug delivery
Lipid-protein interactions

保管および安定性

Liposomes should never be frozen. Liposomes should be stored in the dark at 4°C, except when brought to room temperature for brief periods prior to use.

Liposomes are made under sterile conditions. If you need to take multiple aliquots out of the vial, it is advised to take extreme care in not contaminating the vial. It is recommended to handle the vial under a sterile hood to maintain the sterility of the product. Liposomes should never be frozen. Ice crystals that form during freezing will rupture the lipid membrane of the liposomes and change the size of liposomes particles.

法的情報

Cellsome is a trademark of Encapsula NanoSciences

Product of Encapsula Nanosciences

免責事項

For research use only

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable