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348147

サルササポゲニン

Name: サルササポゲニン
Brand: ALDRICH

95%

別名:

(25S)-スピロスタン-3β-オール, パリゲニン

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About This Item

実験式（ヒル表記法）:

C₂₇H₄₄O₃

CAS番号:

126-19-2

分子量:

416.64

MDL番号:

MFCD00270414

UNSPSCコード:

12352200

PubChem Substance ID:

329755058

アッセイ

95%

フォーム

solid

SMILES記法

C[C@H]1CC[C@@]2(OC1)O[C@H]3C[C@H]4[C@@H]5CC[C@@H]6C[C@@H](O)CC[C@]6(C)[C@H]5CC[C@]4(C)[C@H]3[C@@H]2C

InChI

1S/C27H44O3/c1-16-7-12-27(29-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(28)8-10-25(18,3)21(20)9-11-26(22,24)4/h16-24,28H,5-15H2,1-4H3/t16-,17-,18+,19-,20+,21-,22-,23-,24-,25-,26-,27+/m0/s1

InChI Key

GMBQZIIUCVWOCD-WWASVFFGSA-N

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Lot/Batch Number

07202HW

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Inhibitory effects of steroidal timosaponins isolated from the rhizomes of Anemarrhena asphodeloides against passive cutaneous anaphylaxis reaction and pruritus.

Bomi Lee et al.

Immunopharmacology and immunotoxicology, 32(3), 357-363 (2010-01-26)

To investigate the antiallergic effect of the rhizome of Anemarrhena asphodeloides (AA, family Liliaceae), which was found to inhibit the mouse passive cutaneous anaphylaxis (PCA) reaction induced by the antigen-immunoglobulin E (IgE) complex in preliminary experiments, main steroidal saponins, timosaponins

Deacylation reactions of 20-acetyl dinorcholanic lactones and 20,23-diacetyl furost-22-enes.

Ma Guadalupe Hernández-Linares et al.

Steroids, 75(3), 240-244 (2009-12-26)

We report the deacylation of (20R)-20-acetyl-23,24-dinorcholanic lactones by hydrazine hydrate, under microwave irradiation in high yields. The elimination of the 20-acetyl group proceeded with retention of configuration which contrast with other proved deacylation methods that yield a mixture of diastereoisomers.

The protective potential of Yucca schidigera (Sarsaponin 30) against nitrite-induced oxidative stress in rats.

I Hakki Cigerci et al.

Journal of natural medicines, 63(3), 311-317 (2009-05-13)

The present study was designed to determine the protective effects of Yucca schidigera (Ys) against oxidative damage induced by acute nitrite intoxication as well as the histopathological evaluation of Ys in rats. The rats were divided into three groups each

[Studies on accumulation of active ingredients, N, P and K in Anemarrhena asphodeloides].

Juan Chen et al.

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 32(15), 1504-1507 (2007-11-02)

To study the accumulation of active ingredients, the absorption and transformation of N, P and K in Anemarrhena asphodeloides and provide basis for determination of the harvest time and fertilizing. Samples were collected in different phrases and the weight of

Smilagenin attenuates beta amyloid (25-35)-induced degeneration of neuronal cells via stimulating the gene expression of brain-derived neurotrophic factor.

R Zhang et al.

Neuroscience, 210, 275-285 (2012-03-24)

The development of drugs that attenuate neurodegeneration is important for the treatment of Alzheimer's disease (AD). We previously found that smilagenin (SMI), a steroidal sapogenin from traditional Chinese medicinal herbs improves memory in animal models, is neither a cholinesterase inhibitor