TCF3
transcription factor 3
別名:
E2A, E47, ITF1, TCF-3, VDIR, bHLHb21
Species:
Human TCF3 (6929), Mouse Tcf3 (21423), Rat Tcf3 (171046), domestic guinea pig Tcf3 (100733634), naked mole-rat Tcf3 (101725133), cow TCF3 (530616), Horse TCF3 (100147220), sheep TCF3 (100913162), dog TCF3 (485079), domestic cat TCF3 (101098930)
UniProtKB ID:
遺伝子ID:
- Human(6929) Summary: This gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1;19), with PBX1), childhood leukemia (t(19;19), with TFPT) and acute leukemia (t(12;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Sep 2011]
- Mouse(21423) transcription factor 3
- Rat(171046) transcription factor 3
- domestic guinea pig(100733634) transcription factor 3
- naked mole-rat(101725133) transcription factor 3
- cow(530616) transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
- Horse(100147220) transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
- sheep(100913162) transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
- dog(485079) transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
- domestic cat(101098930) transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
- chicken(395146) transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
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Antibodies
製品番号
詳細
交差性
アプリケーション
抗TCF3抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
western blot
western blot
抗TCF3抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
immunohistochemistry
抗TCF3抗体 ウサギ宿主抗体, affinity isolated antibody, buffered aqueous solution,
交差性
human, mouse, rat
アプリケーション
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Monoclonal Anti-TCF3, (C-terminal) antibody produced in mouse, clone 5G2, ascites fluid,
交差性
human
アプリケーション
ELISA
western blot
western blot