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Merck

TAPBP

TAP binding protein (tapasin)

別名:
NGS17, TAPA, TPN, TPSN
Species:
UniProtKB ID:
遺伝子ID:
  • Human(6892) Summary: This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(21356) TAP binding protein
  • Rat(25217) TAP binding protein (tapasin)
  • dog(481740) TAP binding protein (tapasin)
  • naked mole-rat(101719224) TAP binding protein (tapasin)
  • chicken(417048) TAP binding protein (tapasin)
  • Zebrafish(30163) TAP binding protein
  • domestic cat(101091023) TAP binding protein (tapasin)
  • sheep(100170652) TAP binding protein (tapasin)
  • domestic guinea pig(100735947) TAP binding protein (tapasin)
  • Horse(100061515) TAP binding protein (tapasin)
  • cow(504335) TAP binding protein (tapasin)

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Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-Tapasin Antibody, clone 7F6, clone 7F6, from rat,
交差性
human
アプリケーション
flow cytometry
Anti-TAPBP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Anti-TAPBP antibody produced in rabbit, affinity isolated antibody,
交差性
human
アプリケーション
immunohistochemistry
western blot
Anti-TAPBP antibody produced in rabbit, affinity isolated antibody,
交差性
bovine, horse, human, mouse, pig, rat, sheep
アプリケーション
western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human TAPBP (2),
Species
human
MISSION® esiRNA, targeting human TAPBP (1),
Species
human