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Merck

STAT5B

signal transducer and activator of transcription 5B

別名:
STAT5
Species:
UniProtKB ID:
遺伝子ID:
  • Human(6777) Summary: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq, Jul 2008]
  • Mouse(20851) signal transducer and activator of transcription 5B
  • Rat(25126) signal transducer and activator of transcription 5B
  • domestic cat(101090663) signal transducer and activator of transcription 5B
  • chicken(395556) signal transducer and activator of transcription 5B
  • domestic guinea pig(100716532) signal transducer and activator of transcription 5B
  • naked mole-rat(101722721) signal transducer and activator of transcription 5B
  • cow(282376) signal transducer and activator of transcription 5B
  • sheep(101122961) signal transducer and activator of transcription 5B
  • dog(490969) signal transducer and activator of transcription 5B

Custom & Knockdown Gene Products

ELISA

製品番号
詳細
Species
Cell-Based ELISA for detecting phospho-STAT5 (pTyr694) in cultured cell lines, 96 assays,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-STAT5B Antibody, clone 2G13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
交差性
bovine, feline, human, monkey, porcine, rat
アプリケーション
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
抗STAT5B抗体 (ab2) ウサギ宿主抗体, affinity isolated antibody,
交差性
dog, horse, human, mouse, pig, rabbit, rat
アプリケーション
immunohistochemistry
western blot
ANTI-STAT5B antibody produced in mouse, clone 1F5, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot
Anti-STAT5B Antibody, Upstate®, from rabbit,
交差性
human, mouse
アプリケーション
western blot
Anti-acetyl STAT5B (Lys701) Antibody, from rabbit, purified by affinity chromatography,
交差性
human
アプリケーション
dot blot
western blot

Proteins

製品番号
詳細
Species
STAT5B Protein, recombinant,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human STAT5B,
Species
human
MISSION® esiRNA, targeting mouse Stat5b,
Species
mouse