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Merck

SRD5A2

steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)

別名:
Species:
UniProtKB ID:
遺伝子ID:
  • Human(6716) Summary: This gene encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH). [provided by RefSeq, Jul 2008]
  • Mouse(94224) steroid 5 alpha-reductase 2
  • Rat(64677) steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
  • sheep(100820756) steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
  • chicken(772291) steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
  • naked mole-rat(101708836) steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
  • domestic cat(101086898) steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
  • dog(403715) steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
  • domestic guinea pig(100731664) steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
  • cow(527024) steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)

Custom & Knockdown Gene Products

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-SRD5A2, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
交差性
bovine, dog, horse, human
アプリケーション
western blot
Anti-SRD5A2 (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
交差性
canine, human, rat
アプリケーション
ELISA
western blot
Monoclonal Anti-SRD5A2 antibody produced in mouse, clone 1F4, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot
Anti-SRD5A2 antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
フィナステリド, United States Pharmacopeia (USP) Reference Standard,
Species
human
フィナステリド, European Pharmacopoeia (EP) Reference Standard,
Species
human
フィナステリド, European Pharmacopoeia (EP) Reference Standard,
Species
human
フィナステリド, British Pharmacopoeia (BP) Reference Standard,
Species
human
デュタステリド, ≥98% (HPLC),
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human SRD5A2,
Species
human