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Merck

SPTBN2

spectrin, beta, non-erythrocytic 2

別名:
GTRAP41, SCA5, SCAR14
Species:
UniProtKB ID:
遺伝子ID:
  • Human(6712) Summary: Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements. [provided by RefSeq, Dec 2009]
  • Mouse(20743) spectrin beta, non-erythrocytic 2
  • Rat(29211) spectrin, beta, non-erythrocytic 2
  • sheep(101106728) spectrin, beta, non-erythrocytic 2
  • domestic guinea pig(100731189) spectrin, beta, non-erythrocytic 2
  • dog(483706) spectrin, beta, non-erythrocytic 2
  • Zebrafish(322068) spectrin, beta, non-erythrocytic 2
  • cow(100336865) spectrin, beta, non-erythrocytic 2
  • naked mole-rat(101714181) spectrin, beta, non-erythrocytic 2
  • Domestic Rabbit(100355265) spectrin, beta, non-erythrocytic 2
  • domestic cat(101089045) spectrin, beta, non-erythrocytic 2
  • cow(100336410) spectrin, beta, non-erythrocytic 2

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Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-SPTBN2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Anti-SPTBN2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
Monoclonal Anti-SPTBN2 antibody produced in mouse, clone 4D9, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot
Anti-Spectrin antibody produced in rabbit, whole antiserum,
交差性
human
アプリケーション
western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human SPTBN2,
Species
human