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Merck

SNTA1

syntrophin, alpha 1

別名:
LQT12, SNT1, TACIP1, dJ1187J4.5
Species:
UniProtKB ID:
遺伝子ID:
  • Human(6640) Summary: Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex. This gene is a member of the syntrophin gene family and encodes the most common syntrophin isoform found in cardiac tissues. The N-terminal PDZ domain of this syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1.5. This protein also associates cardiac sodium channels with the nitric oxide synthase-PMCA4b (plasma membrane Ca-ATPase subtype 4b) complex in cardiomyocytes. This gene is a susceptibility locus for Long-QT syndrome (LQT) - an inherited disorder associated with sudden cardiac death from arrhythmia - and sudden infant death syndrome (SIDS). This protein also associates with dystrophin and dystrophin-related proteins at the neuromuscular junction and alters intracellular calcium ion levels in muscle tissue. [provided by RefSeq, Jan 2013]
  • Mouse(20648) syntrophin, acidic 1
  • Rat(362242) syntrophin, alpha 1
  • sheep(101109469) syntrophin, alpha 1
  • Domestic Rabbit(100009179) syntrophin, alpha 1
  • cow(527488) syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)
  • domestic cat(101098944) syntrophin, alpha 1
  • dog(485837) syntrophin, alpha 1
  • domestic guinea pig(100732931) syntrophin, alpha 1
  • naked mole-rat(101721241) syntrophin, alpha 1

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Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-Syntrophin alpha 1 antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
western blot
Anti-SNTA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
Anti-α1-Syntrophin (RA-16) antibody produced in rabbit, buffered aqueous solution, IgG fraction of antiserum,
交差性
rat
アプリケーション
immunohistochemistry
microarray

western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human SNTA1,
Species
human