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Merck

SMARCA4

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

別名:
BAF190, BAF190A, BRG1, MRD16, RTPS2, SNF2, SNF2L4, SNF2LB, SWI2, hSNF2b
Species:
UniProtKB ID:
遺伝子ID:
  • Human(6597) Summary: The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
  • Mouse(20586) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  • Rat(171379) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  • dog(476710) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  • sheep(101116565) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  • domestic cat(101097046) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  • Zebrafish(353295) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  • chicken(395932) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  • cow(414274) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  • naked mole-rat(101700987) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  • domestic guinea pig(100719729) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

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Antibodies

製品番号
詳細
交差性
アプリケーション
抗BRG1抗体 クローン1N12 ZooMAb® ウサギ・モノクローナル, recombinant, expressed in HEK 293 cells,
交差性
human, mouse
アプリケーション
immunocytochemistry
immunohistochemistry

western blot
Anti-SNF2β/BRG1 Antibody, serum, Upstate®,
交差性
human, mouse, rat
アプリケーション
immunoprecipitation (IP)
western blot
Anti-SMARCA4 Antibody, clone 20C3.2, clone 20C3.2, from mouse,
交差性
human, rat
アプリケーション
immunocytochemistry
western blot
Anti-SMARCA4 antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
western blot
Anti-BRG1/SMARCA4 Antibody, clone 20C3.2 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
交差性
human, rat
アプリケーション
immunocytochemistry
immunohistochemistry

western blot

Proteins

製品番号
詳細
Species
BRG1、野生型 ヒト, recombinant, expressed in insect cells, ≥80% (SDS-PAGE),
Species
human
BRG1 (1480-1603) His tag human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human SMARCA4,
Species
human