SLC22A5
solute carrier family 22 (organic cation/carnitine transporter), member 5
CDSP, OCTN2, OCTN2VT
Human SLC22A5 (6584), Mouse Slc22a5 (20520), Rat Slc22a5 (29726), chicken SLC22A5 (416328), chicken SLC22A5 (101664718), Horse SLC22A5 (100072871), domestic cat SLC22A5 (101084417), dog SLC22A5 (608146), Domestic Rabbit SLC22A5 (100358417), sheep SLC22A5 (101122785) ...詳細
- Human(6584) Summary: Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is a plasma integral membrane protein which functions both as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. The encoded protein is involved in the active cellular uptake of carnitine. Mutations in this gene are the cause of systemic primary carnitine deficiency (CDSP), an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy. [provided by RefSeq, Jul 2008]
- Mouse(20520) solute carrier family 22 (organic cation transporter), member 5
- Rat(29726) solute carrier family 22 (organic cation/carnitine transporter), member 5
- chicken(416328) solute carrier family 22 (organic cation transporter), member 5
- chicken(101664718) solute carrier family 22 (organic cation/carnitine transporter), member 5
- Horse(100072871) solute carrier family 22 (organic cation/carnitine transporter), member 5
- domestic cat(101084417) solute carrier family 22 (organic cation/carnitine transporter), member 5
- dog(608146) solute carrier family 22 (organic cation/carnitine transporter), member 5
- Domestic Rabbit(100358417) solute carrier family 22 (organic cation/carnitine transporter), member 5
- sheep(101122785) solute carrier family 22 (organic cation/carnitine transporter), member 5
- cow(541266) solute carrier family 22 (organic cation/carnitine transporter), member 5
- naked mole-rat(101720927) solute carrier family 22 (organic cation/carnitine transporter), member 5
- domestic guinea pig(100719297) solute carrier family 22 (organic cation/carnitine transporter), member 5
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Antibodies
Anti-SLC22A5 antibody produced in rabbit, affinity isolated antibody,
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immunohistochemistry
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western blot