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Merck

SIGLEC8

sialic acid binding Ig-like lectin 8

別名:
SAF2, SIGLEC-8, SIGLEC8L
Species:
Human SIGLEC8 (27181), Rat Siglec8 (292846), sheep SIGLEC8 (101123144)
UniProtKB ID:
Q9NYZ4, Q7Z728
遺伝子ID:
  • Human(27181) Summary: Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein (SAP; MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]
  • Rat(292846) sialic acid binding Ig-like lectin 8
  • sheep(101123144) sialic acid binding Ig-like lectin 8

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Antibodies

製品番号
詳細
交差性
アプリケーション
HPA012556
抗SIGLEC8抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
western blot
WH0027181M3
Monoclonal Anti-Siglec-8 antibody produced in mouse, clone 3H1, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot
SAB2500942
抗SIGLEC8抗体 ヤギ宿主抗体, affinity isolated antibody, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot

esiRNA

製品番号
詳細
Species
EHU074421
MISSION® esiRNA, targeting human SIGLEC8,
Species
human