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Merck

RASGRF1

Ras protein-specific guanine nucleotide-releasing factor 1

別名:
CDC25, CDC25L, GNRP, GRF1, GRF55, H-GRF55, PP13187, ras-GRF1
Species:
UniProtKB ID:
遺伝子ID:
  • Human(5923) Summary: The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Mar 2009]
  • Mouse(19417) RAS protein-specific guanine nucleotide-releasing factor 1
  • Rat(192213) RAS protein-specific guanine nucleotide-releasing factor 1
  • Horse(100050202) Ras protein-specific guanine nucleotide-releasing factor 1
  • chicken(415578) Ras protein-specific guanine nucleotide-releasing factor 1
  • naked mole-rat(101699491) Ras protein-specific guanine nucleotide-releasing factor 1
  • domestic cat(101092941) Ras protein-specific guanine nucleotide-releasing factor 1
  • cow(520039) Ras protein-specific guanine nucleotide-releasing factor 1
  • sheep(101113014) Ras protein-specific guanine nucleotide-releasing factor 1
  • domestic guinea pig(100731687) Ras protein-specific guanine nucleotide-releasing factor 1
  • dog(488774) Ras protein-specific guanine nucleotide-releasing factor 1

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Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-RASGRF1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
Anti-RASGRF1 (S929) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
immunohistochemistry
Anti-phospho-Ras-GRF1 (pSer916) antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunohistochemistry
Anti-Phospho-RASGRF1-S929 antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
dot blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human RASGRF1,
Species
human
MISSION® esiRNA, targeting mouse Rasgrf1,
Species
mouse