コンテンツへスキップ
Merck

PTPRJ

protein tyrosine phosphatase, receptor type, J

別名:
CD148, DEP1, HPTPeta, R-PTP-ETA, SCC1
Species:
Human PTPRJ (5795), Mouse Ptprj (19271), Rat Ptprj (29645), chicken PTPRJ (395330), Domestic Rabbit PTPRJ (100347798), domestic cat PTPRJ (101086598), dog PTPRJ (483617), Horse PTPRJ (100058689), cow PTPRJ (508150), sheep PTPRJ (101121292) ...詳細
UniProtKB ID:
Q12913, Q15255, Q6P4H4, Q8NHM2, Q9UDA9
遺伝子ID:
  • Human(5795) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(19271) protein tyrosine phosphatase, receptor type, J
  • Rat(29645) protein tyrosine phosphatase, receptor type, J
  • chicken(395330) protein tyrosine phosphatase, receptor type, J
  • Domestic Rabbit(100347798) protein tyrosine phosphatase, receptor type, J
  • domestic cat(101086598) protein tyrosine phosphatase, receptor type, J
  • dog(483617) protein tyrosine phosphatase, receptor type, J
  • Horse(100058689) protein tyrosine phosphatase, receptor type, J
  • cow(508150) protein tyrosine phosphatase, receptor type, J
  • sheep(101121292) protein tyrosine phosphatase, receptor type, J
  • domestic guinea pig(100729887) protein tyrosine phosphatase, receptor type, J
  • naked mole-rat(101726039) protein tyrosine phosphatase, receptor type, J

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

製品番号
詳細
Species
RAB1414
Human DEP-1 ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
SAB4701121
Monoclonal Anti-CD148-APC antibody produced in mouse, clone MEM-CD148/05,
交差性
アプリケーション
flow cytometry
MABF2070
Anti-Protein-tyrosine phosphatase eta (CD148) Antibody, clone 8A-1, clone 8A-1, from hamster(Syrian),
交差性
mouse
アプリケーション
flow cytometry
immunohistochemistry
western blot
HPA006026
抗PTPRJ ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
SAB4700728
Monoclonal Anti-CD148 antibody produced in mouse, clone MEM-CD148/05, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
flow cytometry
MABC87
Anti-CD148/DEP-1 Antibody, clone Ab1 (Azide Free), clone Ab 1, from mouse,
交差性
human, mouse
アプリケーション
immunohistochemistry
immunoprecipitation (IP)
inhibition assay
western blot

Proteins

製品番号
詳細
Species
SRP0220
DEP1 Active human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Species
human

esiRNA

製品番号
詳細
Species
EMU094441
MISSION® esiRNA, targeting mouse Ptprj,
Species
mouse
EHU016811
MISSION® esiRNA, targeting human PTPRJ,
Species
human