PTPRC
protein tyrosine phosphatase, receptor type, C
別名:
B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200
Species:
Human PTPRC (5788), Mouse Ptprc (19264), Rat Ptprc (24699), Zebrafish ptprc (559154), chicken PTPRC (386580), domestic cat PTPRC (101097123), Horse PTPRC (100061950), dog PTPRC (490255), sheep PTPRC (101102917), cow PTPRC (407152) ...詳細
UniProtKB ID:
遺伝子ID:
- Human(5788) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]
- Mouse(19264) protein tyrosine phosphatase, receptor type, C
- Rat(24699) protein tyrosine phosphatase, receptor type, C
- Zebrafish(559154) protein tyrosine phosphatase, receptor type, C
- chicken(386580) protein tyrosine phosphatase, receptor type, C
- domestic cat(101097123) protein tyrosine phosphatase, receptor type, C
- Horse(100061950) protein tyrosine phosphatase, receptor type, C
- dog(490255) protein tyrosine phosphatase, receptor type, C
- sheep(101102917) protein tyrosine phosphatase, receptor type, C
- cow(407152) protein tyrosine phosphatase, receptor type, C
- Domestic Rabbit(100358807) protein tyrosine phosphatase, receptor type, C
- naked mole-rat(101710515) protein tyrosine phosphatase, receptor type, C
- domestic guinea pig(100730564) protein tyrosine phosphatase, receptor type, C
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Antibodies
製品番号
詳細
交差性
アプリケーション
Anti-CD45.1 (Mouse), violetFluor® 450, clone A20 Antibody, clone A20, from mouse, violetFluor® 450,
交差性
mouse
アプリケーション
flow cytometry
Anti-CD45 Antibody, clone IBL-5/25, clone IBL-5/25, from rat,
交差性
mouse
アプリケーション
flow cytometry
immunohistochemistry
immunohistochemistry
Small Molecule - Inhibitor
Proteins
製品番号
詳細
Species
CD45 Active human, recombinant, expressed in baculovirus infected insect cells, ≥90% (SDS-PAGE),
Species
human
CD45 Protein, 10 µg, His6-tagged, recombinant, human CD45, amino acids 598-end, for use in Enzyme Assays.,
Species
human
PTPRC (592-end)、活性型、GSTタグ融合 マウス由来, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
mouse