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Merck

PRKCE

protein kinase C, epsilon

別名:
PKCE, nPKC-epsilon
Species:
UniProtKB ID:
遺伝子ID:
  • Human(5581) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior. [provided by RefSeq, Jul 2008]
  • Mouse(18754) protein kinase C, epsilon
  • Rat(29340) protein kinase C, epsilon
  • chicken(421409) protein kinase C, epsilon
  • domestic cat(101100958) protein kinase C, epsilon
  • dog(609934) protein kinase C, epsilon
  • cow(507041) protein kinase C, epsilon
  • Horse(100053394) protein kinase C, epsilon
  • Domestic Rabbit(100009103) protein kinase C, epsilon
  • sheep(101110314) protein kinase C, epsilon
  • naked mole-rat(101700837) protein kinase C, epsilon
  • domestic guinea pig(100721814) protein kinase C, epsilon

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Small Molecule - Agonist

製品番号
詳細
Species
オレイン酸, ≥99% (GC),
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-PKCε Antibody, Upstate®, from rabbit,
交差性
human, mouse, rat
アプリケーション
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-PRKCE antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
western blot
Anti-phospho-PKCepsilon Antibody (Ser729), from rabbit, purified by affinity chromatography,
交差性
human, mouse, rat
アプリケーション
western blot
Anti-PRKCE antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
Anti-PRKCE antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence

Small Molecule - Inhibitor

製品番号
詳細
Species
H-7 二塩酸塩, ≥98% (HPLC),
Species
human
タモキシフェン クエン酸塩, ≥99%,
Species
human
オレイン酸, ≥99% (GC),
Species
human
UCN-01, ≥97% (HPLC), powder,
Species
human
GSK690693, ≥98% (HPLC),
Species
human

Proteins

製品番号
詳細
Species
PKCε Protein, active, 10 µg, Active, N-terminal His6-tagged, recombinant PKCε, amino acids 2-end. For use in Kinase Assays.,
Species
human
PKC ε、活性型、GSTタグ融合 ヒト, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting mouse Prkce,
Species
mouse
MISSION® esiRNA, targeting human PRKCE,
Species
human