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Merck

PRKCB

protein kinase C, beta

別名:
PKC-beta, PKCB, PRKCB1, PRKCB2
Species:
UniProtKB ID:
遺伝子ID:
  • Human(5579) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(18751) protein kinase C, beta
  • Rat(25023) protein kinase C, beta
  • Domestic Rabbit(100037719) protein kinase C, beta
  • sheep(101118410) protein kinase C, beta
  • naked mole-rat(101722702) protein kinase C, beta
  • domestic cat(101088970) protein kinase C, beta
  • chicken(416567) protein kinase C, beta
  • dog(489968) protein kinase C, beta
  • cow(282325) protein kinase C, beta

Custom & Knockdown Gene Products

Small Molecule - Agonist

製品番号
詳細
Species
オレイン酸, ≥99% (GC),
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-PRKCB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
Anti-p-PKCβ (Ser660) Antibody, clone 2C11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
交差性
bovine, human, monkey, mouse, rabbit, rat
アプリケーション
affinity binding assay
immunocytochemistry

inhibition assay

western blot
Anti-PKCβ Antibody, clone 2E13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
交差性
human, monkey, mouse
アプリケーション
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-PRKCB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
Anti-Phospho-PKCalpha/beta II-T638/641 antibody produced in rabbit, ,
交差性
human
アプリケーション
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
ヒスピジン, solid, ≥98% (HPLC),
Species
human
H-7 二塩酸塩, ≥98% (HPLC),
Species
human
タモキシフェン クエン酸塩, ≥99%,
Species
human
オレイン酸, ≥99% (GC),
Species
human
UCN-01, ≥97% (HPLC), powder,
Species
human

Proteins

製品番号
詳細
Species
プロテインキナーゼ CβIIアイソザイム ヒト, >85% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting mouse Prkcb,
Species
mouse
MISSION® esiRNA, targeting human PRKCB,
Species
human