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Merck

PLCG1

phospholipase C, gamma 1

別名:
NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1
Species:
UniProtKB ID:
遺伝子ID:
  • Human(5335) Summary: The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(18803) phospholipase C, gamma 1
  • Rat(25738) phospholipase C, gamma 1
  • naked mole-rat(101705192) phospholipase C, gamma 1
  • chicken(419175) phospholipase C, gamma 1
  • dog(485874) phospholipase C, gamma 1
  • Zebrafish(373867) phospholipase C, gamma 1
  • domestic cat(101092925) phospholipase C, gamma 1
  • cow(281987) phospholipase C, gamma 1
  • domestic guinea pig(100716986) phospholipase C, gamma 1
  • sheep(101103341) phospholipase C, gamma 1

Custom & Knockdown Gene Products

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-PLCγ-1 Antibody, Upstate®, from mouse,
交差性
bovine, human, mouse, rabbit, rat
アプリケーション
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-Phospho-PLC gamma 1 (PLCG1)-Y783 antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
western blot
Anti-PLCG1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry

western blot
Anti-PLCγ-1 Antibody, clone B-6-4, clone B-6-4, 1 mg/mL, Upstate®,
交差性
bovine, human, mouse, rabbit, rat
アプリケーション
immunoprecipitation (IP)
western blot
Monoclonal Anti-PLCG1 antibody produced in mouse, clone 2A2, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
immunofluorescence

proximity ligation assay

western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human PLCG1,
Species
human
MISSION® esiRNA, targeting mouse Plcg1,
Species
mouse