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Merck

PITX2

paired-like homeodomain 2

別名:
ARP1, Brx1, IDG2, IGDS, IGDS2, IHG2, IRID2, Otlx2, PTX2, RGS, RIEG, RIEG1, RS
Species:
UniProtKB ID:
遺伝子ID:
  • Human(5308) Summary: This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
  • Mouse(18741) paired-like homeodomain transcription factor 2
  • Rat(54284) paired-like homeodomain 2
  • naked mole-rat(101722303) paired-like homeodomain 2
  • sheep(101116988) paired-like homeodomain 2
  • cow(506721) paired-like homeodomain 2
  • domestic cat(101081219) paired-like homeodomain 2
  • Horse(100146441) paired-like homeodomain 2
  • dog(487902) paired-like homeodomain 2
  • chicken(395862) paired-like homeodomain 2
  • Zebrafish(30164) paired-like homeodomain transcription factor 2
  • domestic guinea pig(100715589) paired-like homeodomain 2

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Antibodies

製品番号
詳細
交差性
アプリケーション
Monoclonal Anti-PITX2 antibody produced in mouse, clone 2G6, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
immunofluorescence

western blot
抗PITX2抗体, IgG fraction of antiserum,
交差性
bovine, human, mouse, pig
アプリケーション
immunohistochemistry
western blot
Anti-PITX2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
Anti-PITX2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human PITX2,
Species
human