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Merck

PIK3C2A

phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha

別名:
CPK, PI3-K-C2(ALPHA), PI3-K-C2A
Species:
UniProtKB ID:
遺伝子ID:
  • Human(5286) Summary: The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling. [provided by RefSeq, Jul 2008]
  • Mouse(18704) phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide
  • Rat(361632) phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
  • sheep(101114899) phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
  • Zebrafish(571356) phosphoinositide-3-kinase, class 2, alpha polypeptide
  • domestic cat(101096512) phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
  • cow(537790) phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
  • chicken(423070) phosphoinositide-3-kinase, class 2, alpha polypeptide
  • naked mole-rat(101702206) phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
  • Domestic Rabbit(100340704) phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
  • Horse(100056431) phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
  • dog(485399) phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
  • domestic guinea pig(100722144) phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha

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Antibodies

製品番号
詳細
交差性
アプリケーション
抗PIK3C2A抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
抗PIK3C2A抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Anti-PI3KC2A (N-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot
抗PIK3C2A抗体 ヤギ宿主抗体, affinity isolated antibody, buffered aqueous solution,
交差性
human, mouse
アプリケーション
ELISA
immunohistochemistry
ANTI-PI3KC2A(N-TERMINAL) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
交差性
human
アプリケーション
western blot

Proteins

製品番号
詳細
Species
PIK3C2A, active, GST tagged human, PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human PIK3C2A,
Species
human
MISSION® esiRNA, targeting mouse Pik3c2a,
Species
mouse