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Merck

PARK2

parkinson protein 2, E3 ubiquitin protein ligase (parkin)

別名:
AR-JP, LPRS2, PDJ, PRKN
Species:
UniProtKB ID:
遺伝子ID:
  • Human(5071) Summary: The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq, Jul 2008]
  • Mouse(50873) Parkinson disease (autosomal recessive, juvenile) 2, parkin
  • Rat(56816) parkinson protein 2, E3 ubiquitin protein ligase
  • cow(530858) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
  • naked mole-rat(101700770) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
  • domestic guinea pig(100724550) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
  • Horse(100057832) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
  • Zebrafish(550328) Parkinson disease (autosomal recessive, juvenile) 2, parkin
  • chicken(421577) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
  • dog(612316) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
  • domestic cat(101098228) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
  • sheep(101113503) parkinson protein 2, E3 ubiquitin protein ligase (parkin)

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Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-Parkin Antibody, clone PRK8, ascites fluid, clone PRK8, Upstate®,
交差性
human, mouse
アプリケーション
immunocytochemistry
immunohistochemistry

immunoprecipitation (IP)

western blot
抗PARK2抗体 ヤギ宿主抗体, affinity isolated antibody, buffered aqueous solution,
交差性
canine, human, mouse, rat
アプリケーション
ELISA
western blot
ANTI-PARKIN(C-TERMINAL) antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
交差性
human, mouse
アプリケーション
flow cytometry
immunofluorescence

immunohistochemistry

western blot
Anti-Parkin antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunohistochemistry

western blot
Anti-Parkin Antibody, a.a. 305-323, serum, Chemicon®,
交差性
human, rat
アプリケーション
ELISA
immunohistochemistry

western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human PARK2,
Species
human