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Merck

NR1H4

nuclear receptor subfamily 1, group H, member 4

別名:
BAR, FXR, HRR-1, HRR1, RIP14
Species:
Human NR1H4 (9971), Mouse Nr1h4 (20186), Rat Nr1h4 (60351), domestic cat NR1H4 (101096997), naked mole-rat Nr1h4 (101714263), cow NR1H4 (540528), domestic guinea pig Nr1h4 (100734377), Zebrafish nr1h4 (436847), Horse NR1H4 (100052821), chicken NR1H4 (373902) ...詳細
UniProtKB ID:
Q96RI1, A1L4K5, B7Z412, B7ZM06, F8VYG8, Q8NFP5, Q8NFP6, Q92943
遺伝子ID:
  • Human(9971) Summary: This gene encodes a ligand-activated transcription factor, which shares structural features in common with nuclear hormone receptor family, such as a DNA-binding domain that targets the receptor to specific DNA sequences, and a ligand-binding domain, which interacts directly with the ligand and contains a ligand-dependent transcriptional activation domain. This protein functions as a receptor for bile acids, and when bound to bile acids, regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
  • Mouse(20186) nuclear receptor subfamily 1, group H, member 4
  • Rat(60351) nuclear receptor subfamily 1, group H, member 4
  • domestic cat(101096997) nuclear receptor subfamily 1, group H, member 4
  • naked mole-rat(101714263) nuclear receptor subfamily 1, group H, member 4
  • cow(540528) nuclear receptor subfamily 1, group H, member 4
  • domestic guinea pig(100734377) nuclear receptor subfamily 1, group H, member 4
  • Zebrafish(436847) nuclear receptor subfamily 1, group H, member 4
  • Horse(100052821) nuclear receptor subfamily 1, group H, member 4
  • chicken(373902) nuclear receptor subfamily 1, group H, member 4
  • dog(612928) nuclear receptor subfamily 1, group H, member 4
  • sheep(101105401) nuclear receptor subfamily 1, group H, member 4
  • Domestic Rabbit(100009485) nuclear receptor subfamily 1, group H, member 4

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Small Molecule - Agonist

製品番号
詳細
Species
U5127
ウルソデオキシコール酸, ≥99%,
Species
human
1707806
ウルソデオキシコール酸, United States Pharmacopeia (USP) Reference Standard,
Species
human
BP926
ケノデオキシコール酸, British Pharmacopoeia (BP) Reference Standard,
Species
human
PHR1579
ウルソデオキシコール酸, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
C1050000
ケノデオキシコール酸, European Pharmacopoeia (EP) Reference Standard,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
AV33672
抗NR1H4抗体 ウサギ宿主抗体, affinity isolated antibody,
交差性
bovine, dog, guinea pig, horse, human, mouse, rat
アプリケーション
immunohistochemistry
western blot
WH0009971M1
Monoclonal Anti-NR1H4 antibody produced in mouse, clone 1G11, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
immunofluorescence
western blot
AB10305
Anti-FXR-B Antibody, serum, Chemicon®,
交差性
human
アプリケーション
western blot
SAB1404768
Monoclonal Anti-NR1H4, (C-terminal) antibody produced in mouse, clone 1B10, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
immunofluorescence
western blot
SAB2500384
抗ファルネソイドXレセプター/HRR1抗体 ヤギ宿主抗体, affinity isolated antibody, buffered aqueous solution,
交差性
canine, human
アプリケーション
ELISA
western blot

esiRNA

製品番号
詳細
Species
EMU026301
MISSION® esiRNA, targeting mouse Nr1h4,
Species
mouse
EHU133161
MISSION® esiRNA, targeting human NR1H4,
Species
human