NACA
nascent polypeptide-associated complex alpha subunit
別名:
NACA1
Species:
Human NACA (4666), Mouse Naca (17938), Rat Naca (288770), domestic cat NACA (101087933), chicken NACA (396544), sheep NACA (101105899), Zebrafish naca (195823), dog NACA (474408), cow NACA (513312), domestic guinea pig Naca (100730848)
UniProtKB ID:
遺伝子ID:
- Human(4666) Summary: The protein encoded by this gene associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). NAC binds to nascent proteins as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. However, nascent proteins with an exposed signal peptide will not be bound by the encoded protein, enabling them to bind the SRP and enter the secretory pathway. This protein has been determined to be an IgE autoantigen in atopic dermatitis patients. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
- Mouse(17938) nascent polypeptide-associated complex alpha polypeptide
- Rat(288770) nascent polypeptide-associated complex alpha subunit
- domestic cat(101087933) nascent polypeptide-associated complex alpha subunit
- chicken(396544) nascent polypeptide-associated complex alpha subunit
- sheep(101105899) nascent polypeptide-associated complex alpha subunit
- Zebrafish(195823) nascent polypeptide-associated complex alpha polypeptide
- dog(474408) nascent polypeptide-associated complex alpha subunit
- cow(513312) nascent polypeptide-associated complex alpha subunit
- domestic guinea pig(100730848) nascent polypeptide-associated complex alpha subunit
- naked mole-rat(101700724) nascent polypeptide-associated complex alpha subunit
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