コンテンツへスキップ
Merck

MTRR

5-methyltetrahydrofolate-homocysteine methyltransferase reductase

別名:
MSR, cblE
Species:
UniProtKB ID:
遺伝子ID:
  • Human(4552) Summary: Methionine is an essential amino acid required for protein synthesis and one-carbon metabolism. Its synthesis is catalyzed by the enzyme methionine synthase. Methionine synthase eventually becomes inactive due to the oxidation of its cob(I)alamin cofactor. The protein encoded by this gene regenerates a functional methionine synthase via reductive methylation. It is a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. Patients of the cbl-E complementation group of disorders of folate/cobalamin metabolism are defective in reductive activation of methionine synthase. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(210009) 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
  • Rat(290947) 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
  • domestic guinea pig(100732821) 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
  • Zebrafish(560667) 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
  • chicken(428502) 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
  • sheep(101123409) 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
  • Domestic Rabbit(100350605) 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
  • cow(507991) 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
  • domestic cat(101098359) 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
  • dog(478623) 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
  • naked mole-rat(101720530) 5-methyltetrahydrofolate-homocysteine methyltransferase reductase

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-MTRR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Monoclonal Anti-MTRR antibody produced in mouse, clone 1G7, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human MTRR,
Species
human