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Merck

MTA2

metastasis associated 1 family, member 2

別名:
MTA1L1, PID
Species:
UniProtKB ID:
遺伝子ID:
  • Human(9219) Summary: This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacetylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis. [provided by RefSeq, May 2011]
  • Mouse(23942) metastasis-associated gene family, member 2
  • Rat(361724) metastasis associated 1 family, member 2
  • domestic guinea pig(100732932) metastasis associated 1 family, member 2
  • Zebrafish(326078) metastasis associated 1 family, member 2
  • Domestic Rabbit(100351042) metastasis associated 1 family, member 2
  • Goat(100861363) metastasis associated 1 family, member 2
  • sheep(101111404) metastasis associated 1 family, member 2
  • cow(515389) metastasis associated 1 family, member 2
  • domestic cat(101086925) metastasis associated 1 family, member 2
  • Horse(100063490) metastasis associated 1 family, member 2
  • dog(476057) metastasis associated 1 family, member 2

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Antibodies

製品番号
詳細
交差性
アプリケーション
抗MTA2抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human, mouse, rat
アプリケーション
immunofluorescence
immunohistochemistry

western blot
Anti- MTA2 antibody produced in rabbit, ,
交差性
all
アプリケーション
western blot
Anti-MTA2, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
交差性
bovine, dog, goat, guinea pig, horse, human, mouse, rabbit, rat
アプリケーション
western blot
Anti-MTA2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
western blot
Anti- MTA2 antibody produced in rabbit, ,
交差性
human, rat
アプリケーション
immunohistochemistry
western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting mouse Mta2,
Species
mouse
MISSION® esiRNA, targeting human MTA2,
Species
human
MISSION® esiRNA, targeting mouse Mta2,
Species
mouse