MASP1
mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
別名:
3MC1, CRARF, CRARF1, MAP1, MASP, MASP3, MAp44, PRSS5, RaRF
Species:
Human MASP1 (5648), Mouse Masp1 (17174), Rat Masp1 (64023), sheep MASP1 (101111065), cow MASP1 (522347), Zebrafish masp1 (100002060), Horse MASP1 (100068261), domestic cat MASP1 (101097166), naked mole-rat Masp1 (101716867), dog MASP1 (488121) ...詳細
UniProtKB ID:
遺伝子ID:
- Human(5648) Summary: This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010]
- Mouse(17174) mannan-binding lectin serine peptidase 1
- Rat(64023) mannan-binding lectin serine peptidase 1
- sheep(101111065) mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
- cow(522347) mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
- Zebrafish(100002060) mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
- Horse(100068261) mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
- domestic cat(101097166) mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
- naked mole-rat(101716867) mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
- dog(488121) mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
- domestic guinea pig(100730575) mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
- chicken(407088) mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
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ELISA
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詳細
Species
Human CMASP-3 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
human
Antibodies
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交差性
アプリケーション
抗MASP1抗体 ウサギ宿主抗体, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
抗MASP1抗体, affinity isolated antibody,
交差性
human, mouse
アプリケーション
immunohistochemistry
western blot
western blot
esiRNA
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Species