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Merck

MAP3K12

mitogen-activated protein kinase kinase kinase 12

別名:
DLK, MEKK12, MUK, ZPK, ZPKP1
Species:
UniProtKB ID:
遺伝子ID:
  • Human(7786) Summary: This gene encodes a member of the serine/threonine protein kinase family. This kinase contains a leucine-zipper domain and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation. Alternatively spliced transcript variants encoding different proteins have been described.[provided by RefSeq, Jul 2010]
  • Mouse(26404) mitogen-activated protein kinase kinase kinase 12
  • Rat(25579) mitogen activated protein kinase kinase kinase 12
  • naked mole-rat(101702332) mitogen-activated protein kinase kinase kinase 12
  • chicken(101669120) mitogen-activated protein kinase kinase kinase 12
  • Horse(100064002) mitogen-activated protein kinase kinase kinase 12
  • Zebrafish(404626) mitogen-activated protein kinase kinase kinase 12
  • chicken(101750914) mitogen-activated protein kinase kinase kinase 12
  • domestic cat(101087164) mitogen-activated protein kinase kinase kinase 12
  • cow(505427) mitogen-activated protein kinase kinase kinase 12
  • sheep(101102889) mitogen-activated protein kinase kinase kinase 12
  • Domestic Rabbit(100358158) mitogen-activated protein kinase kinase kinase 12
  • dog(607170) mitogen-activated protein kinase kinase kinase 12
  • domestic guinea pig(100731317) mitogen-activated protein kinase kinase kinase 12

Custom & Knockdown Gene Products

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-MAP3K12 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Anti-MAP3K12 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
ANTI-MAP3K12 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
western blot

Proteins

製品番号
詳細
Species
DLK, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human MAP3K12,
Species
human
MISSION® esiRNA, targeting mouse Map3k12,
Species
mouse